HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 1025
+	Hs
		932216 ACTC_HUMAN (2-375): 0: 592: 94.12		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		1153256 POTEE_HUMAN (1-375): 0: 736: 92.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		724859 ACTBL_HUMAN (2-375): 0: 735: 91.71		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		892089 ACTB_HUMAN (1-375): 0: 603: 100.00		SWP70_HUMAN (370-824): 7.27e-58: 212: 19.22
+	Hs
		929935 ACTG_HUMAN (1-375): 0: 601: 98.93		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		929898 ACTG_HUMAN (1-375): 0: 601: 98.93		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		932211 ACTC_HUMAN (2-375): 0: 592: 94.12		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		148662 ACTC_HUMAN (2-375): 0: 592: 94.12		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Mm
		892205 ACTB_MOUSE (1-375): 0: 603: 100.00		MYH9_MOUSE (542-1025): 4.68e-18: 92.5: 8.68
+	Rn
		892228 ACTB_RAT (1-375): 0: 603: 100.00		MYH9_RAT (566-1025): 4.61e-18: 92.5: 9.81
+	Hs
		724738 ACTB_HUMAN (1-375): 0: 603: 100.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724762 ACTG_HUMAN (1-375): 0: 601: 98.93		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Rn
		892236 ACTB_RAT (1-375): 0: 603: 100.00		MYH10_RAT (534-1014): 1.07e-15: 84.8: 11.32
+	Hs
		724766 ACTC_HUMAN (2-375): 0: 592: 94.12		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724767 ACTS_HUMAN (2-375): 0: 592: 93.58		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		725136 ACTC_HUMAN (2-375): 0: 592: 94.12		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		929869 ACTG_HUMAN (1-375): 0: 601: 98.93		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		255307 ACTB_HUMAN (1-375): 0: 603: 100.00		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56
+	Hs
		932171 ACTC_HUMAN (2-375): 0: 592: 94.12		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Mm
		930101 ACTH_MOUSE (2-375): 0: 589: 93.58		PLEC_MOUSE (494-979): 2.14e-11: 70.8: 14.60