HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0015629 - actin cytoskeleton
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1098
+	Hs
		930050 ACTG_HUMAN (1-375): 0: 601: 98.93		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Mm
		929790 ACTG_MOUSE (1-375): 0: 601: 98.93		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Rn
		192517 ACTB_RAT (1-375): 0: 603: 100.00		NEB2_RAT (1-826): 2.53e-45: 178: 43.42
+	Mm
		892184 ACTB_MOUSE (1-375): 0: 603: 100.00		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		891987 ACTB_HUMAN (1-375): 0: 603: 100.00		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Hs
		929975 ACTG_HUMAN (1-375): 0: 601: 98.93		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Rn
		192522 ACTS_RAT (2-375): 0: 592: 93.58		NEB2_RAT (1-826): 2.53e-45: 178: 43.42
+	Mm
		932490 ACTC_MOUSE (2-375): 0: 592: 94.12		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		933086 ACTS_MOUSE (2-375): 0: 592: 93.58		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		933041 ACTS_HUMAN (2-375): 0: 592: 93.58		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Hs
		915484 ACTA_HUMAN (2-375): 0: 591: 94.12		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Mm
		892179 ACTB_MOUSE (1-375): 0: 603: 100.00		INADL_MOUSE (133-693): 1.79e-14: 80.9: 10.80