HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: TTF2 (Q9UNY4)
Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)
Gene: TTF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1162
+	Hs
		846794 ACTBL_HUMAN (2-375): 0: 735: 91.71		SMCA2_HUMAN (117-1159): 1.87e-177: 565: 16.00
+	Hs
		891731 ACTB_HUMAN (1-375): 0: 603: 100.00		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Hs
		929837 ACTG_HUMAN (1-375): 0: 601: 98.93		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Hs
		932125 ACTC_HUMAN (2-375): 0: 592: 94.12		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Hs
		846910 ACTB_HUMAN (1-375): 0: 603: 100.00		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Hs
		846917 ACTG_HUMAN (1-375): 0: 601: 98.93		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Mm
		929785 ACTG_MOUSE (1-375): 0: 601: 98.93		SMCA4_MOUSE (113-1159): 0: 593: 17.18
+	Dm
		501486 ACT1_DROME (2-375): 0: 598: 98.13		BRM_DROME (125-1162): 0: 590: 16.07
+	Dm
		361138 ACT2_DROME (2-375): 0: 596: 97.59		BRM_DROME (125-1162): 0: 590: 16.07
+	Hs
		846918 ACTC_HUMAN (2-375): 0: 592: 94.12		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Hs
		846919 ACTS_HUMAN (2-375): 0: 592: 93.58		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Mm
		929795 ACTG_MOUSE (1-375): 0: 601: 98.93		SMCA2_MOUSE (118-1159): 0: 578: 16.71
+	Hs
		891769 ACTB_HUMAN (1-375): 0: 603: 100.00		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Xl
		292752 ACTB_XENLA (1-375): 0: 602: 99.47		Q4VQ79_XENLA (132-1159): 1.1e-176: 563: 16.83
+	Hs
		932158 ACTC_HUMAN (2-375): 0: 592: 94.12		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Hs
		846742 ACTC_HUMAN (2-375): 0: 592: 94.12		SMCA2_HUMAN (117-1159): 1.87e-177: 565: 16.00
+	Hs
		229358 ACTC_HUMAN (2-375): 0: 592: 94.12		SMCA5_HUMAN (452-1162): 1.14e-175: 546: 20.03
+	Zm
		13638 A0A1D6FW13_MAIZE (3-375): 0: 588: 89.28		A0A1D6MT91_MAIZE (438-1159): 1.16e-172: 541: 20.11
+	Sp
		194292 ACT_SCHPO (1-375): 0: 592: 90.40		FFT3_SCHPO (548-1148): 4.54e-34: 144: 26.70