HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: DUS10 (Q9Y6W6)
Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5)
Gene: DUSP10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 482
+	Hs
		1122545 ACTBL_HUMAN (2-375): 0: 735: 91.71		DUS10_HUMAN (1-482): 0: 632: 100.00
+	Hs
		932483 ACTC_HUMAN (2-375): 0: 592: 94.12		DUS10_HUMAN (1-482): 0: 632: 100.00
+	Hs
		915547 ACTA_HUMAN (2-375): 0: 591: 94.12		DUS10_HUMAN (1-482): 0: 632: 100.00
+	Hs
		1122454 ACTBL_HUMAN (2-375): 0: 735: 91.71		DUS19_HUMAN (304-475): 2.81e-55: 185: 33.72
+	Hs
		1122455 ACTBL_HUMAN (2-375): 0: 735: 91.71		STYX_HUMAN (321-473): 2.48e-54: 183: 33.54
+	Hs
		915497 ACTA_HUMAN (2-375): 0: 591: 94.12		DUS16_HUMAN (161-475): 5.3e-96: 305: 33.33
+	Hs
		1122460 ACTBL_HUMAN (2-375): 0: 735: 91.71		SSH1_HUMAN (325-459): 6.96e-20: 95.1: 39.26
+	Hs
		474837 POTEI_HUMAN (1-375): 0: 731: 91.20		SSH1_HUMAN (325-459): 6.96e-20: 95.1: 39.26
+	Hs
		933079 ACTS_HUMAN (2-375): 0: 592: 93.58		STYL1_HUMAN (172-473): 5.11e-63: 209: 20.50
+	Hs
		933023 ACTS_HUMAN (2-375): 0: 592: 93.58		SSH3_HUMAN (291-479): 2.41e-59: 208: 26.98
+	Hs
		891859 ACTB_HUMAN (1-375): 0: 603: 100.00		SSH2_HUMAN (292-481): 1.08e-53: 196: 27.37
+	Hs
		891921 ACTB_HUMAN (1-375): 0: 603: 100.00		DUS19_HUMAN (304-475): 2.81e-55: 185: 33.72
+	Hs
		929942 ACTG_HUMAN (1-375): 0: 601: 98.93		DUS19_HUMAN (304-475): 2.81e-55: 185: 33.72
+	Hs
		933025 ACTS_HUMAN (2-375): 0: 592: 93.58		DUS19_HUMAN (304-475): 2.81e-55: 185: 33.72
+	Hs
		915454 ACTA_HUMAN (2-375): 0: 591: 94.12		DUS19_HUMAN (304-475): 2.81e-55: 185: 33.72
+	Hs
		891931 ACTB_HUMAN (1-375): 0: 603: 100.00		SSH1_HUMAN (325-459): 6.96e-20: 95.1: 39.26
+	Hs
		933027 ACTS_HUMAN (2-375): 0: 592: 93.58		SSH1_HUMAN (325-459): 6.96e-20: 95.1: 39.26
+	Hs
		915459 ACTA_HUMAN (2-375): 0: 591: 94.12		SSH1_HUMAN (325-459): 6.96e-20: 95.1: 39.26