HitPredict

Interactor 1: ACTB (P60710)
Actin, cytoplasmic 1 (Beta-actin) (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: PLST (Q99K51)
Plastin-3 (T-plastin)
Gene: Pls3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31189591
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005737 - cytoplasm GO:0005884 - actin filament
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Mm			1 630
+	Hs
		533285 ACTB_HUMAN (1-375): 0: 603: 100.00		PLST_HUMAN (1-630): 0: 664: 99.05
+	Hs
		533292 ACTG_HUMAN (1-375): 0: 601: 98.93		PLST_HUMAN (1-630): 0: 664: 99.05
+	Hs
		533207 ACTB_HUMAN (1-375): 0: 603: 100.00		PLSL_HUMAN (4-630): 0: 628: 79.75
+	Hs
		533209 ACTG_HUMAN (1-375): 0: 601: 98.93		PLSL_HUMAN (4-630): 0: 628: 79.75
+	Hs
		891766 ACTB_HUMAN (1-375): 0: 603: 100.00		PLSI_HUMAN (3-630): 0: 620: 75.48
+	Hs
		533210 ACTC_HUMAN (2-375): 0: 592: 94.12		PLSL_HUMAN (4-630): 0: 628: 79.75
+	Hs
		506816 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTB1_HUMAN (73-630): 2.35e-130: 424: 16.12
+	Hs
		891697 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTB2_HUMAN (74-630): 1.15e-127: 417: 15.98
+	Hs
		929824 ACTG_HUMAN (1-375): 0: 601: 98.93		SPTB2_HUMAN (74-630): 1.15e-127: 417: 15.98
+	Hs
		164588 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTN2_HUMAN (384-628): 2.33e-56: 209: 23.62
+	Hs
		211548 ACTB_HUMAN (1-375): 0: 603: 100.00		ACTN4_HUMAN (381-628): 6.47e-56: 206: 20.78
+	Hs
		725637 ACTB_HUMAN (1-375): 0: 603: 100.00		ACTN2_HUMAN (393-628): 8.41e-54: 199: 20.58
+	Hs
		211560 ACTC_HUMAN (2-375): 0: 592: 94.12		ACTN4_HUMAN (381-628): 6.47e-56: 206: 20.78
+	Hs
		211561 ACTS_HUMAN (2-375): 0: 592: 93.58		ACTN4_HUMAN (381-628): 6.47e-56: 206: 20.78
+	Hs
		891706 ACTB_HUMAN (1-375): 0: 603: 100.00		DYST_HUMAN (393-622): 1.48e-43: 170: 23.83
+	Hs
		892113 ACTB_HUMAN (1-375): 0: 603: 100.00		MACF1_HUMAN (380-622): 7.88e-43: 168: 22.18
+	Hs
		929869 ACTG_HUMAN (1-375): 0: 601: 98.93		PLEC_HUMAN (393-630): 1.66e-43: 170: 22.95
+	Dm
		284844 ACT1_DROME (2-375): 0: 598: 98.13		O77291_DROME (393-622): 7.33e-40: 159: 22.22
+	Hs
		513848 ACTS_HUMAN (2-375): 0: 592: 93.58		DMD_HUMAN (119-384): 2.15e-40: 161: 21.56
+	Sp
		223801 ACT_SCHPO (1-375): 0: 592: 90.40		FIMB_SCHPO (397-624): 1.82e-20: 97.5: 22.66