HitPredict

Interactor 1: ACTB (P60711)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: WASF1 (Q5BJU7)
Actin-binding protein WASF1 (Protein WAVE-1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	16530190
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0005925 - focal adhesion GO:0030027 - lamellipodium GO:0032991 - protein-containing complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 375 Rn			1 559
+	Hs
		929950 ACTG_HUMAN (1-375): 0: 601: 98.93		WASF1_HUMAN (1-559): 2.86e-80: 263: 97.50
+	Hs
		846794 ACTBL_HUMAN (2-375): 0: 735: 91.71		SMCA2_HUMAN (224-542): 1.46e-23: 107: 13.86
+	Hs
		554315 ACTBL_HUMAN (2-375): 0: 735: 91.71		MUC1_HUMAN (209-551): 1.85e-09: 62.8: 12.61
+	Hs
		930055 ACTG_HUMAN (1-375): 0: 601: 98.93		WASF3_HUMAN (1-557): 6.27e-55: 195: 45.98
+	Hs
		892150 ACTB_HUMAN (1-375): 0: 603: 100.00		WASF2_HUMAN (1-541): 9.26e-47: 172: 42.51
+	Hs
		930077 ACTG_HUMAN (1-375): 0: 601: 98.93		WASF2_HUMAN (1-541): 9.26e-47: 172: 42.51
+	Hs
		932482 ACTC_HUMAN (2-375): 0: 592: 94.12		WASF2_HUMAN (1-541): 9.26e-47: 172: 42.51
+	Mm
		929795 ACTG_MOUSE (1-375): 0: 601: 98.93		SMCA2_MOUSE (192-542): 2.87e-25: 113: 11.28
+	Hs
		891942 ACTB_HUMAN (1-375): 0: 603: 100.00		CBP_HUMAN (164-530): 6.35e-22: 102: 15.15
+	Hs
		891979 ACTB_HUMAN (1-375): 0: 603: 100.00		EP400_HUMAN (186-524): 1.9e-21: 101: 15.34
+	Mm
		929800 ACTG_MOUSE (1-375): 0: 601: 98.93		EP400_MOUSE (162-525): 1.27e-21: 102: 14.36
+	Hs
		929972 ACTG_HUMAN (1-375): 0: 601: 98.93		EP400_HUMAN (186-524): 1.9e-21: 101: 15.34
+	Hs
		846742 ACTC_HUMAN (2-375): 0: 592: 94.12		SMCA2_HUMAN (224-542): 1.46e-23: 107: 13.86
+	Hs
		915464 ACTA_HUMAN (2-375): 0: 591: 94.12		CBP_HUMAN (164-530): 6.35e-22: 102: 15.15
+	Hs
		932332 ACTC_HUMAN (2-375): 0: 592: 94.12		EP400_HUMAN (186-524): 1.9e-21: 101: 15.34
+	Hs
		554290 ACTA_HUMAN (2-375): 0: 591: 94.12		MUC1_HUMAN (209-551): 1.85e-09: 62.8: 12.61