HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 1675
+	Hs
		925199 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		545326 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		960973 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		950928 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		893908 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		900383 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		436257 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		564482 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Dm
		669565 RAC1_DROME (1-192): 2.16e-81: 241: 89.06		CLH_DROME (1-1663): 0: 2911: 80.17