HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1202
+	Hs
		925243 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		545349 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		1025343 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		950961 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		893955 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		900430 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		925488 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		545537 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		724757 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		892521 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		894274 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		724776 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		925406 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		545475 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		1203019 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		725138 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29
+	Hs
		892463 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		725125 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29
+	Hs
		951125 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		894179 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62