HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: IQGA2 (Q13576)
Ras GTPase-activating-like protein IQGAP2
Gene: IQGAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 31871319, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RasGAP
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030027 - lamellipodium
GO:0032956 - regulation of actin cytoskeleton organization
GO:0070062 - extracellular exosome
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 192
Hs

1 1575
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024