HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 998
+	Hs
		925297 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		545394 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		1072595 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		872423 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		545285 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		872418 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		665387 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		EPHA3_HUMAN (25-990): 0: 1189: 62.01
+	Hs
		892660 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		EPHA6_HUMAN (6-998): 0: 1163: 56.44
+	Hs
		665201 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		545218 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		665332 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		665191 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		665208 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		872522 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		545286 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		872575 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		872515 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		412123 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45
+	Hs
		789109 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		FRK_HUMAN (611-886): 1.46e-62: 223: 41.01
+	Hs
		411980 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45