HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: SWAHC (Q53LP3)
Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)
Gene: SOWAHC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 525
+	Hs
		925328 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		951048 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		894087 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		925238 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		925204 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ANK2_HUMAN (260-522): 2.09e-37: 150: 14.77
+	Hs
		950953 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		893947 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		900423 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		276162 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		PSD10_HUMAN (275-408): 8.79e-40: 145: 26.12
+	Mm
		892714 RAC3_MOUSE (1-192): 5.54e-79: 235: 100.00		ANS1B_MOUSE (266-509): 8.36e-33: 135: 15.36
+	Hs
		925723 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		545696 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		1330985 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		892676 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		951454 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		894580 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Mm
		82719 RAC3_MOUSE (1-192): 5.54e-79: 235: 100.00		CTTB2_MOUSE (82-366): 1.81e-20: 97.7: 11.25
+	Hs
		925249 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		1033553 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		893969 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29