HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: RGPA1 (Q6GYQ0)
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)
Gene: RALGAPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 2036
+	Hs
		925359 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		1151779 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		951081 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		894131 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		900583 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		564573 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		1102438 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		RGPA2_HUMAN (1-2030): 0: 2671: 49.46
+	Hs
		951036 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		RGPA2_HUMAN (1-2030): 0: 2671: 49.46
+	Hs
		564550 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		RGPA2_HUMAN (1-2030): 0: 2671: 49.46
+	Hs
		925514 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91
+	Hs
		900790 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91
+	Hs
		925407 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		1203741 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		230233 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Hs
		892464 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Dm
		776929 RAC1_DROME (1-192): 2.16e-81: 241: 89.06		X2JDH0_DROME (1637-2013): 4.12e-102: 367: 21.16
+	Dm
		776932 RAC1_DROME (1-192): 2.16e-81: 241: 89.06		X2JJU0_DROME (1637-2013): 3.69e-102: 367: 21.16
+	Hs
		951126 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		894180 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		900651 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67