HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0030036 - actin cytoskeleton organization GO:0032956 - regulation of actin cytoskeleton organization
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 1708
+	Hs
		925368 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		545453 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		1163856 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		951091 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		894144 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		900603 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		436365 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		564579 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		RICTR_HUMAN (1-1708): 0: 2775: 100.00