HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: AMGO2 (Q86SJ2)
Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA)
Gene: AMIGO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 522
+	Hs
		925398 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		AMGO2_HUMAN (1-522): 1.07e-85: 276: 100.00
+	Hs
		545469 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		AMGO2_HUMAN (1-522): 1.07e-85: 276: 100.00
+	Hs
		1197727 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		AMGO2_HUMAN (1-522): 1.07e-85: 276: 100.00
+	Hs
		951118 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		AMGO2_HUMAN (1-522): 1.07e-85: 276: 100.00
+	Hs
		894171 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		AMGO2_HUMAN (1-522): 1.07e-85: 276: 100.00
+	Hs
		564592 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		AMGO2_HUMAN (1-522): 1.07e-85: 276: 100.00
+	Hs
		894276 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		PXDN_HUMAN (2-480): 2.77e-32: 134: 11.13
+	Hs
		302720 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96
+	Hs
		302707 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96
+	Hs
		302740 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96
+	Hs
		302715 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96
+	Hs
		265889 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		LGR5_HUMAN (41-208): 9.81e-20: 95.1: 36.99
+	Hs
		302721 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96
+	Hs
		302716 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96
+	Hs
		302717 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96
+	Hs
		302704 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96
+	Hs
		302708 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		SLIK5_HUMAN (40-239): 9.58e-16: 82.4: 33.96