HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0030027 - lamellipodium GO:0030426 - growth cone GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 508
+	Hs
		925427 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		545489 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		925670 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		545658 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Dm
		776930 RAC1_DROME (1-192): 2.16e-81: 241: 89.06		RHGF_DROME (65-505): 9.11e-39: 152: 14.97
+	Hs
		925724 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		925240 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MYO1E_HUMAN (305-503): 2.96e-27: 118: 22.67
+	Hs
		587801 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		NCF2_HUMAN (211-501): 2.81e-27: 117: 12.29
+	Hs
		166043 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SYNJ2_HUMAN (39-458): 2.1e-26: 115: 13.88
+	Hs
		545347 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MYO1E_HUMAN (305-503): 2.96e-27: 118: 22.67
+	Hs
		1021704 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		MYO1E_HUMAN (305-503): 2.96e-27: 118: 22.67
+	Hs
		545204 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		NCF2_HUMAN (211-501): 2.81e-27: 117: 12.29
+	Hs
		892342 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		MYO1E_HUMAN (305-503): 2.96e-27: 118: 22.67
+	Hs
		166039 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		SYNJ2_HUMAN (39-458): 2.1e-26: 115: 13.88
+	Hs
		297823 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		K0754_HUMAN (80-400): 5.9e-17: 86.7: 7.60
+	Hs
		297812 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		K0754_HUMAN (80-400): 5.9e-17: 86.7: 7.60
+	Hs
		297840 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		K0754_HUMAN (80-400): 5.9e-17: 86.7: 7.60
+	Hs
		297819 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		K0754_HUMAN (80-400): 5.9e-17: 86.7: 7.60
+	Hs
		925460 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SH3R3_HUMAN (324-507): 1.44e-09: 62.9: 16.13
+	Hs
		925396 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SH3R1_HUMAN (244-503): 3.15e-09: 61.6: 17.28