HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: SL9A6 (Q92581)
Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6)
Gene: SLC9A6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 701
+	Hs
		586027 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Hs
		545203 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Hs
		586069 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Hs
		586021 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Hs
		586031 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Hs
		586022 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Hs
		586024 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Hs
		436155 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Hs
		564409 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		SL9A1_HUMAN (116-686): 2.1e-148: 453: 22.52
+	Dm
		1177641 Q7JWS8_DROME (2-192): 3.86e-81: 240: 67.54		Q9VCS7_DROME (95-543): 1.78e-56: 204: 15.94