HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 2054
+	Hs
		925488 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		545537 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		894274 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		900754 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		564633 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		724757 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		724776 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		545482 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		MY18B_HUMAN (1024-1700): 3.43e-34: 146: 11.13
+	Hs
		925728 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MYO5B_HUMAN (1603-2051): 4.65e-14: 80.6: 9.19
+	Hs
		725138 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		725125 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		564757 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		MYO5A_HUMAN (1789-2053): 7.86e-13: 76.7: 12.84