HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: HCD2 (Q99714)
3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-estradiol 17-dehydrogenase) (EC 1.1.1.62) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))) (EC 1.1.1.239) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (3alpha(or 20beta)-hydroxysteroid dehydrogenase) (EC 1.1.1.53) (7-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.159) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH)
Gene: HSD17B10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 261
+	Hs
		925557 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		HCD2_HUMAN (1-261): 4.29e-83: 251: 100.00
+	Hs
		1305823 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		HCD2_HUMAN (1-261): 4.29e-83: 251: 100.00
+	Hs
		951265 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		HCD2_HUMAN (1-261): 4.29e-83: 251: 100.00
+	Hs
		894353 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		HCD2_HUMAN (1-261): 4.29e-83: 251: 100.00
+	Hs
		900838 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		HCD2_HUMAN (1-261): 4.29e-83: 251: 100.00
+	Mm
		139831 RHOA_MOUSE (5-192): 9.79e-77: 229: 54.79		HCD2_MOUSE (1-261): 5.08e-81: 245: 86.21