HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: RFIP5 (Q9BXF6)
Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)
Gene: RAB11FIP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RBD-FIP~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 653
+	Hs
		925583 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		545594 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		1315230 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		951290 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		894384 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Ce
		136793 RAC1_CAEEL (1-192): 1.53e-82: 244: 81.25		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297823 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297812 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297840 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Ce
		104464 G5EBV3_CAEEL (2-192): 2.34e-77: 231: 63.87		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297819 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297827 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297820 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		925372 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		545456 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		1167470 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		892442 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		951094 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		894148 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		900608 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14