HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: TANC1 (Q9C0D5)
Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)
Gene: TANC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0043025 - neuronal cell body GO:0098978 - glutamatergic synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 1861
+	Hs
		925593 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		1319199 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		951308 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		925238 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Hs
		950953 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Hs
		893947 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Hs
		900423 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Hs
		925204 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Hs
		894457 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		TANC2_HUMAN (813-1861): 1.46e-72: 272: 15.17
+	Hs
		925723 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		545696 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		1330985 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		883465 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		RIPK4_HUMAN (629-935): 1.98e-34: 145: 12.14
+	Hs
		892676 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		951454 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		894580 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		901042 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		436568 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		564734 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67