HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: K1549 (Q9HCM3)
UPF0606 protein KIAA1549
Gene: KIAA1549

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1950
+	Hs
		925636 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		K1549_HUMAN (1-1950): 0: 1003: 100.00
+	Hs
		951358 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		K1549_HUMAN (1-1950): 0: 1003: 100.00
+	Hs
		894460 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		K1549_HUMAN (1-1950): 0: 1003: 100.00
+	Hs
		900930 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		K1549_HUMAN (1-1950): 0: 1003: 100.00
+	Ce
		136793 RAC1_CAEEL (1-192): 1.53e-82: 244: 81.25		UNC89_CAEEL (28-525): 1.79e-21: 105: 9.45
+	Ce
		104464 G5EBV3_CAEEL (2-192): 2.34e-77: 231: 63.87		UNC89_CAEEL (28-525): 1.79e-21: 105: 9.45
+	Hs
		925603 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		TARA_HUMAN (2-1051): 4.14e-15: 84.1: 9.01
+	Ce
		136794 CDC42_CAEEL (1-192): 3.66e-75: 225: 67.71		UNC89_CAEEL (28-525): 1.79e-21: 105: 9.45
+	Hs
		297823 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		K0754_HUMAN (2-252): 1.71e-12: 75.6: 8.37
+	Hs
		894095 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		BRD10_HUMAN (122-981): 2.79e-18: 94.3: 14.79
+	Hs
		892586 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		TARA_HUMAN (2-1051): 4.14e-15: 84.1: 9.01
+	Hs
		951324 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		TARA_HUMAN (2-1051): 4.14e-15: 84.1: 9.01
+	Hs
		297812 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		K0754_HUMAN (2-252): 1.71e-12: 75.6: 8.37
+	Hs
		297840 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		K0754_HUMAN (2-252): 1.71e-12: 75.6: 8.37
+	Hs
		297819 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		K0754_HUMAN (2-252): 1.71e-12: 75.6: 8.37
+	Hs
		297827 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		K0754_HUMAN (2-252): 1.71e-12: 75.6: 8.37
+	Hs
		564677 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		TARA_HUMAN (2-1051): 4.14e-15: 84.1: 9.01
+	Hs
		297820 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		K0754_HUMAN (2-252): 1.71e-12: 75.6: 8.37
+	Hs
		297809 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		K0754_HUMAN (2-252): 1.71e-12: 75.6: 8.37
+	Hs
		894572 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MUC12_HUMAN (715-1167): 8.78e-10: 66.4: 9.17