HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: PDXL2 (Q9NZ53)
Podocalyxin-like protein 2 (Endoglycan)
Gene: PODXL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 605
+	Hs
		951406 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		PDXL2_HUMAN (1-605): 0: 678: 100.00
+	Hs
		134462 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		PODXL_HUMAN (140-605): 1.3e-120: 370: 21.38
+	Hs
		134441 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		PODXL_HUMAN (140-605): 1.3e-120: 370: 21.38
+	Hs
		134490 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		PODXL_HUMAN (140-605): 1.3e-120: 370: 21.38
+	Hs
		134457 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		PODXL_HUMAN (140-605): 1.3e-120: 370: 21.38
+	Hs
		134465 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		PODXL_HUMAN (140-605): 1.3e-120: 370: 21.38
+	Hs
		134458 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		PODXL_HUMAN (140-605): 1.3e-120: 370: 21.38
+	Hs
		134459 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		PODXL_HUMAN (140-605): 1.3e-120: 370: 21.38
+	Hs
		134434 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		PODXL_HUMAN (140-605): 1.3e-120: 370: 21.38
+	Hs
		297823 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		K0754_HUMAN (100-388): 3.05e-14: 78.8: 15.48
+	Hs
		297812 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		K0754_HUMAN (100-388): 3.05e-14: 78.8: 15.48
+	Hs
		297840 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		K0754_HUMAN (100-388): 3.05e-14: 78.8: 15.48
+	Hs
		297819 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		K0754_HUMAN (100-388): 3.05e-14: 78.8: 15.48
+	Hs
		297827 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		K0754_HUMAN (100-388): 3.05e-14: 78.8: 15.48
+	Ce
		136793 RAC1_CAEEL (1-192): 1.53e-82: 244: 81.25		UNC89_CAEEL (82-361): 6.69e-10: 64.5: 15.41
+	Hs
		297820 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		K0754_HUMAN (100-388): 3.05e-14: 78.8: 15.48
+	Hs
		297809 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		K0754_HUMAN (100-388): 3.05e-14: 78.8: 15.48
+	Ce
		104464 G5EBV3_CAEEL (2-192): 2.34e-77: 231: 63.87		UNC89_CAEEL (82-361): 6.69e-10: 64.5: 15.41
+	Hs
		867087 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		SC24C_HUMAN (139-375): 5.79e-10: 64.5: 13.41
+	Ce
		136794 CDC42_CAEEL (1-192): 3.66e-75: 225: 67.71		UNC89_CAEEL (82-361): 6.69e-10: 64.5: 15.41