HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: ADDG (Q9UEY8)
Gamma-adducin (Adducin-like protein 70)
Gene: ADD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 706
+	Hs
		925703 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ADDG_HUMAN (1-706): 0: 995: 100.00
+	Hs
		545682 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		ADDG_HUMAN (1-706): 0: 995: 100.00
+	Hs
		1330971 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		ADDG_HUMAN (1-706): 0: 995: 100.00
+	Hs
		951434 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		ADDG_HUMAN (1-706): 0: 995: 100.00
+	Hs
		726026 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ADDB_HUMAN (1-695): 0: 855: 53.19
+	Hs
		725939 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		ADDA_HUMAN (1-695): 0: 851: 49.00
+	Hs
		726057 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		ADDB_HUMAN (1-695): 0: 855: 53.19
+	Hs
		545236 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		ADDA_HUMAN (1-695): 0: 851: 49.00
+	Hs
		726000 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		ADDA_HUMAN (1-695): 0: 851: 49.00
+	Hs
		726025 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		ADDB_HUMAN (1-695): 0: 855: 53.19
+	Hs
		726028 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		ADDB_HUMAN (1-695): 0: 855: 53.19
+	Hs
		725934 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		ADDA_HUMAN (1-695): 0: 851: 49.00
+	Hs
		725946 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		ADDA_HUMAN (1-695): 0: 851: 49.00
+	Hs
		297823 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		K0754_HUMAN (338-693): 1.75e-10: 66.9: 11.65
+	Ce
		136793 RAC1_CAEEL (1-192): 1.53e-82: 244: 81.25		UNC89_CAEEL (479-703): 2.88e-09: 63: 15.90
+	Hs
		297812 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		K0754_HUMAN (338-693): 1.75e-10: 66.9: 11.65
+	Hs
		297840 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		K0754_HUMAN (338-693): 1.75e-10: 66.9: 11.65
+	Hs
		297819 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		K0754_HUMAN (338-693): 1.75e-10: 66.9: 11.65
+	Hs
		297827 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		K0754_HUMAN (338-693): 1.75e-10: 66.9: 11.65
+	Ce
		104464 G5EBV3_CAEEL (2-192): 2.34e-77: 231: 63.87		UNC89_CAEEL (479-703): 2.88e-09: 63: 15.90