HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: S4A7 (Q9Y6M7)
Sodium bicarbonate cotransporter 3 (Electroneutral Na/HCO(3) cotransporter) (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7)
Gene: SLC4A7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 1214
+	Hs
		925775 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		545733 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		1331018 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		951507 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		894643 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		901109 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		436601 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		564763 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		392671 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392728 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392666 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392673 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392667 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392669 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392646 RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74