Interactor 1: DNLI4 (P49917)
DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)
Gene: LIG4
Interactor 2: DCR1C (Q96SD1)
Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (Protein A-SCID) (SNM1 homolog C) (hSNM1C) (SNM1-like protein)
Gene: DCLRE1C
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.73 | 0.55 | 0.635 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23219551, 22529269 |
| Identification Methods | x-ray crystallography, isothermal titration calorimetry, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy, anti bait coimmunoprecipitation, pull down |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005654 - nucleoplasm GO:0006303 - double-strand break repair via nonhomologous end joining GO:0033151 - V(D)J recombination GO:0070419 - nonhomologous end joining complex |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
