HitPredict

Interactor 1: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 28514442, 33961781, 29395067, 35271311
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC4_WD40~DEAD
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0006413 - translational initiation
and 1 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 406
Hs

1 325
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Last updated: 15 Jul 2024