HitPredict

Interactor 1: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1

Interactor 2: IPO11 (Q9UI26)
Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11)
Gene: IPO11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 975
+	Hs
		1051929 IF4A2_HUMAN (4-406): 4.47e-158: 453: 90.32		IPO11_HUMAN (1-975): 0: 643: 100.00
+	Hs
		571625 DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88		IPO11_HUMAN (1-975): 0: 643: 100.00
+	Dm
		972158 IF4A_DROME (6-406): 0: 517: 72.95		Q9VRV9_DROME (4-881): 5.4e-125: 402: 11.85
+	Sc
		485812 IF4A_YEAST (20-406): 8.01e-168: 477: 66.41		KA120_YEAST (1-972): 7.8e-117: 385: 24.38
+	Sc
		485823 IF4A_YEAST (20-406): 8.01e-168: 477: 66.41		SXM1_YEAST (7-973): 1.12e-96: 328: 15.91
+	Hs
		162389 DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88		XPO1_HUMAN (10-972): 1.67e-116: 385: 10.00
+	Hs
		163081 DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33		XPO1_HUMAN (10-972): 1.67e-116: 385: 10.00
+	Sc
		485761 IF4A_YEAST (20-406): 8.01e-168: 477: 66.41		NMD5_YEAST (8-849): 1.88e-89: 310: 15.31
+	Xl
		1146043 Q66JB0_XENLA (2-406): 2.03e-138: 410: 28.92		Q6NS03_XENLA (10-972): 1.34e-111: 371: 9.43
+	Xl
		1155771 Q9I8S3_XENLA (12-406): 2.18e-138: 410: 29.53		Q6NS03_XENLA (10-972): 1.34e-111: 371: 9.43
+	Xl
		1155738 Q801P9_XENLA (12-406): 2.48e-136: 404: 29.03		Q6NS03_XENLA (10-972): 1.34e-111: 371: 9.43
+	Hs
		162420 DDX6_HUMAN (32-402): 1.66e-88: 278: 38.71		XPO1_HUMAN (10-972): 1.67e-116: 385: 10.00
+	Xl
		873114 DDX6_XENLA (32-402): 1.73e-88: 278: 38.71		Q6NS03_XENLA (10-972): 1.34e-111: 371: 9.43