HitPredict

Interactor 1: IF4A1 (P60843)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: Eif4a1

Interactor 2: IF4H (Q9WUK2)
Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein homolog)
Gene: Eif4h

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003743 - translation initiation factor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Mm			1 248
+	Mm
		496133 IF4A2_MOUSE (4-406): 4.47e-158: 453: 90.32		IF4H_MOUSE (1-248): 9.36e-54: 175: 100.00
+	At
		97541 F4JEL4_ARATH (18-384): 3.34e-177: 501: 71.39		RBG7_ARATH (41-117): 1.05e-28: 108: 25.32
+	Hs
		618625 IF4A2_HUMAN (4-406): 4.47e-158: 453: 90.32		IF4B_HUMAN (33-208): 4.58e-32: 125: 32.22
+	Hs
		1031325 IF4A2_HUMAN (4-406): 4.47e-158: 453: 90.32		PABP4_HUMAN (33-126): 1.24e-19: 89.4: 18.75
+	Hs
		516515 IF4A2_HUMAN (4-406): 4.47e-158: 453: 90.32		PABP1_HUMAN (33-206): 1.9e-19: 89: 16.20
+	Hs
		618544 IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75		IF4B_HUMAN (33-208): 4.58e-32: 125: 32.22
+	Hs
		618568 IF4A1_HUMAN (1-406): 1.84e-132: 387: 100.00		IF4B_HUMAN (33-208): 4.58e-32: 125: 32.22
+	Hs
		1048159 DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33		HNRPD_HUMAN (2-213): 1.19e-23: 99.4: 15.49
+	At
		783423 IF4A2_ARATH (5-406): 1.07e-135: 396: 68.41		RBG7_ARATH (41-117): 1.05e-28: 108: 25.32
+	Hs
		1054481 DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33		RBM39_HUMAN (36-210): 1.07e-17: 83.6: 18.18
+	Hs
		571452 DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88		RBM39_HUMAN (36-210): 1.07e-17: 83.6: 18.18
+	Mm
		857323 DDX17_MOUSE (2-406): 1.38e-137: 409: 29.33		TIA1_MOUSE (10-224): 4.88e-17: 81.3: 13.36
+	Mm
		857351 Q8BTS0_MOUSE (10-406): 4.82e-138: 409: 29.88		TIA1_MOUSE (10-224): 4.88e-17: 81.3: 13.36
+	Mm
		936480 DDX5_MOUSE (10-406): 4.68e-138: 409: 29.88		TIAR_MOUSE (10-215): 2.49e-14: 73.6: 9.62
+	Hs
		516391 IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75		PABP1_HUMAN (33-206): 1.9e-19: 89: 16.20
+	Hs
		757611 IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75		RBM39_HUMAN (36-210): 1.07e-17: 83.6: 18.18
+	Hs
		892791 IF4A1_HUMAN (1-406): 1.84e-132: 387: 100.00		PABP4_HUMAN (33-126): 1.24e-19: 89.4: 18.75
+	Hs
		516434 IF4A1_HUMAN (1-406): 1.84e-132: 387: 100.00		PABP1_HUMAN (33-206): 1.9e-19: 89: 16.20
+	Mm
		857295 IF4A1_MOUSE (1-406): 1.84e-132: 387: 100.00		TIA1_MOUSE (10-224): 4.88e-17: 81.3: 13.36
+	Sc
		624037 DBP2_YEAST (2-404): 8.49e-137: 403: 31.63		NSR1_YEAST (30-150): 1.54e-09: 59.4: 21.26