HitPredict

Interactor 1: SNP25 (P60880)
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)
Gene: SNAP25

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	10886332, 30610939
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0008021 - synaptic vesicle GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 206 Hs			1 276
+	Ce
		183449 O62414_CAEEL (1-203): 1.08e-64: 200: 52.20		STX1A_CAEEL (4-276): 2.41e-67: 212: 23.38
+	Mm
		192844 SNP25_MOUSE (1-206): 1.77e-64: 199: 100.00		STX1A_MOUSE (18-273): 2.43e-67: 212: 24.05
+	Rn
		699172 SNP25_RAT (1-206): 1.77e-64: 199: 100.00		STX1A_RAT (18-273): 3.22e-67: 212: 24.05
+	Hs
		893263 SNP25_HUMAN (1-206): 1.77e-64: 199: 100.00		STX1B_HUMAN (4-273): 3.79e-67: 212: 23.19
+	Rn
		893305 SNP25_RAT (1-206): 1.77e-64: 199: 100.00		STX1B_RAT (4-273): 3.79e-67: 212: 23.19
+	Bt
		699168 SNP25_BOVIN (1-206): 1.77e-64: 199: 100.00		STX1A_BOVIN (18-273): 1.1e-66: 211: 24.81
+	Hs
		893278 SNP25_HUMAN (1-206): 1.77e-64: 199: 100.00		STX1A_HUMAN (17-273): 6.81e-67: 211: 23.19
+	Hs
		699251 SNP25_HUMAN (1-206): 1.77e-64: 199: 100.00		STX2_HUMAN (16-272): 3.38e-66: 209: 26.62
+	Rn
		102510 SNP25_RAT (1-206): 1.77e-64: 199: 100.00		STX12_RAT (1-252): 1.72e-65: 207: 94.44
+	Dm
		739422 SNP25_DROME (4-204): 2.89e-62: 194: 60.89		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	Dm
		1098103 Q9VH76_DROME (3-205): 1.5e-59: 187: 58.65		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	Hs
		178460 SNP25_HUMAN (1-206): 1.77e-64: 199: 100.00		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	Hs
		893270 SNP25_HUMAN (1-206): 1.77e-64: 199: 100.00		STX4_HUMAN (6-272): 1.25e-53: 177: 24.27
+	Hs
		893272 SNP25_HUMAN (1-206): 1.77e-64: 199: 100.00		STX3_HUMAN (5-250): 2.56e-53: 176: 25.20
+	Dm
		739424 SNP25_DROME (4-204): 2.89e-62: 194: 60.89		Q7K0X9_DROME (21-274): 3.74e-54: 178: 31.84
+	Rn
		893309 SNP25_RAT (1-206): 1.77e-64: 199: 100.00		STX3_RAT (5-250): 1.06e-51: 172: 25.60
+	Dm
		1178788 Q9VH76_DROME (3-205): 1.5e-59: 187: 58.65		Q7K0X9_DROME (21-274): 3.74e-54: 178: 31.84
+	Dm
		739435 SNP25_DROME (4-204): 2.89e-62: 194: 60.89		Q9VU45_DROME (13-269): 2.95e-49: 166: 28.41
+	Ce
		248220 O62414_CAEEL (1-203): 1.08e-64: 200: 52.20		STX3_CAEEL (22-269): 8.73e-44: 152: 20.64
+	Dm
		739433 SNP25_DROME (4-204): 2.89e-62: 194: 60.89		Q9VR90_DROME (166-256): 7.07e-11: 63.5: 36.26