HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 451
+	Hs
		894363 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		900845 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		925180 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Rn
		933753 RAC1_RAT (1-191): 1.75e-84: 249: 70.31		TBA1A_RAT (1-440): 0: 715: 99.55
+	Bt
		900339 RHOA_BOVIN (5-191): 3.88e-81: 240: 53.48		TBA4A_BOVIN (1-450): 0: 719: 96.44
+	Hs
		933168 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		900365 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		951100 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		436370 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428118 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		893889 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		428120 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		933249 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		900366 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		TBB4B_HUMAN (1-437): 0: 697: 40.96