HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: FGD1 (P98174)
FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)
Gene: FGD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 32203420, 8969170
Identification Methods fluorescent resonance energy transfer, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Ras, Ras~RhoGEF
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030036 - actin cytoskeleton organization
GO:0046847 - filopodium assembly
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024