HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: PFKAP (Q01813)
ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)
Gene: PFKP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 784
+	Hs
		925206 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		900389 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		437798 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437736 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437732 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437737 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437769 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		PFKAM_HUMAN (13-779): 0: 1030: 71.78