HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: DSG1 (Q02413)
Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)
Gene: DSG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31478661
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 1049
+	Hs
		925399 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DSG4_HUMAN (1-1049): 0: 773: 38.52
+	Hs
		564523 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DSG2_HUMAN (2-1048): 0: 742: 32.40
+	Hs
		1048664 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DSG2_HUMAN (2-1048): 0: 742: 32.40
+	Hs
		925270 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DSG2_HUMAN (2-1048): 0: 742: 32.40
+	Hs
		893994 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DSG2_HUMAN (2-1048): 0: 742: 32.40
+	Hs
		950987 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		DSG2_HUMAN (2-1048): 0: 742: 32.40
+	Hs
		580261 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		CADH2_HUMAN (19-489): 1.77e-64: 237: 18.71
+	Hs
		580220 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		CADH2_HUMAN (19-489): 1.77e-64: 237: 18.71
+	Hs
		580224 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		CADH2_HUMAN (19-489): 1.77e-64: 237: 18.71
+	Hs
		521837 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		CADH1_HUMAN (19-485): 8.8e-59: 220: 19.01
+	Hs
		521840 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		CADH1_HUMAN (19-485): 8.8e-59: 220: 19.01
+	Hs
		564530 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DSC3_HUMAN (1-355): 3.07e-35: 147: 20.27
+	Hs
		564486 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DSC2_HUMAN (1-378): 2.26e-32: 138: 18.73
+	Hs
		1055855 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DSC3_HUMAN (1-355): 3.07e-35: 147: 20.27
+	Hs
		894012 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DSC3_HUMAN (1-355): 3.07e-35: 147: 20.27
+	Hs
		971065 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DSC2_HUMAN (1-378): 2.26e-32: 138: 18.73
+	Hs
		925210 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DSC2_HUMAN (1-378): 2.26e-32: 138: 18.73
+	Hs
		893916 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DSC2_HUMAN (1-378): 2.26e-32: 138: 18.73
+	Hs
		950934 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		DSC2_HUMAN (1-378): 2.26e-32: 138: 18.73
+	Hs
		606304 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		CADH3_HUMAN (13-185): 1.95e-13: 77: 17.03