HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: MYO9B (Q13459)
Unconventional myosin-IXb (Unconventional myosin-9b)
Gene: MYO9B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RA~Ras, Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 2157
+	Hs
		900443 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Hs
		436289 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Hs
		564757 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MYO5A_HUMAN (64-1775): 0: 974: 19.82
+	Hs
		925728 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MYO5B_HUMAN (67-1775): 0: 948: 19.62
+	Hs
		1183623 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		MYO5A_HUMAN (64-1775): 0: 974: 19.82
+	Ce
		93900 CDC42_CAEEL (1-191): 1.83e-79: 236: 86.39		F0IWT2_CAEEL (1091-2040): 2.52e-99: 359: 20.33
+	Hs
		70662 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MYO9A_HUMAN (591-2140): 2.11e-83: 308: 20.67
+	Hs
		70663 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		MYO9A_HUMAN (591-2140): 2.11e-83: 308: 20.67
+	Hs
		892610 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		MYO10_HUMAN (792-1023): 2.21e-34: 147: 35.44
+	Hs
		724757 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02
+	Hs
		724776 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02