HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 1630
+	Hs
		564526 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		1050061 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		925273 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		950989 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		900463 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Dm
		776889 RAC1_DROME (1-191): 1.02e-81: 242: 69.27		SCRIB_DROME (1-258): 6.81e-66: 249: 37.98
+	Mm
		925797 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42
+	Hs
		564636 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Hs
		564500 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		951207 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Hs
		564652 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		1021562 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		925239 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		893948 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		950954 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		1301445 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		900424 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		925539 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		894337 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		951251 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06