HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~TPR_2
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0016020 - membrane GO:0032991 - protein-containing complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 412
+	Hs
		950994 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		900465 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		545374 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		436300 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		892370 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		893877 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		FKB1A_HUMAN (101-204): 1.72e-35: 128: 32.41
+	Hs
		684632 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00