HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: KPRA (Q14558)
Phosphoribosyl pyrophosphate synthase-associated protein 1 (PRPP synthase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthase-associated protein) (PAP39)
Gene: PRPSAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 356
+	Hs
		925281 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		KPRA_HUMAN (1-356): 1.02e-168: 476: 100.00
+	Hs
		225864 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		KPRB_HUMAN (1-356): 1.88e-168: 475: 78.43
+	Hs
		893330 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PRPS1_HUMAN (7-354): 2.56e-168: 473: 42.98
+	Hs
		225861 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		KPRB_HUMAN (1-356): 1.88e-168: 475: 78.43
+	Hs
		515831 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PRPS2_HUMAN (7-354): 2.87e-166: 468: 43.27
+	Hs
		893326 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		PRPS1_HUMAN (7-354): 2.56e-168: 473: 42.98
+	Hs
		515828 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		PRPS2_HUMAN (7-354): 2.87e-166: 468: 43.27
+	Hs
		893391 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		PRPS1_HUMAN (7-354): 2.56e-168: 473: 42.98