HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: SWAHC (Q53LP3)
Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)
Gene: SOWAHC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 525
+	Hs
		925328 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		951048 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		900544 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		925238 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		925204 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ANK2_HUMAN (260-522): 2.09e-37: 150: 14.77
+	Hs
		893947 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		950953 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		900423 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		564734 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		276162 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		PSD10_HUMAN (275-408): 8.79e-40: 145: 26.12
+	Hs
		900638 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ANS1B_HUMAN (266-509): 1.16e-33: 138: 15.36
+	Hs
		1330985 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		925723 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		894580 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		951454 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		564510 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		1033553 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		925249 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		893969 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		900439 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29