HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: FBP1L (Q5T0N5)
Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1)
Gene: FNBP1L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	15260990, 31478661, 31871319
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0051491 - positive regulation of filopodium assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 605
+	Hs
		1132435 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		FBP1L_HUMAN (1-605): 9.46e-125: 382: 100.00
+	Hs
		925339 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FBP1L_HUMAN (1-605): 9.46e-125: 382: 100.00
+	Hs
		564653 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		FNBP1_HUMAN (1-605): 1.1e-101: 323: 53.96
+	Hs
		1301540 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		FNBP1_HUMAN (1-605): 1.1e-101: 323: 53.96
+	Hs
		925540 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FNBP1_HUMAN (1-605): 1.1e-101: 323: 53.96
+	Hs
		564542 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		CIP4_HUMAN (1-599): 1.04e-94: 304: 50.58
+	Hs
		1075815 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		CIP4_HUMAN (1-599): 1.04e-94: 304: 50.58
+	Hs
		564730 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Hs
		253311 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		SRGP2_HUMAN (6-445): 4.29e-58: 212: 13.67
+	Hs
		1330981 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Hs
		925717 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Hs
		200213 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SRGP3_HUMAN (5-448): 7.41e-59: 215: 14.26
+	Hs
		564496 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		FCHO2_HUMAN (3-559): 3.1e-53: 197: 12.97
+	Hs
		253337 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SRGP2_HUMAN (6-445): 4.29e-58: 212: 13.67
+	Hs
		925395 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SRGP1_HUMAN (6-451): 2.62e-57: 210: 13.54
+	Hs
		925192 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RHG04_HUMAN (1-452): 2.73e-57: 209: 14.55
+	Hs
		1001594 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		FCHO2_HUMAN (3-559): 3.1e-53: 197: 12.97
+	Hs
		925230 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FCHO2_HUMAN (3-559): 3.1e-53: 197: 12.97
+	Hs
		564738 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		PACN2_HUMAN (303-595): 6.96e-20: 94.9: 12.50
+	Hs
		1330988 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		PACN2_HUMAN (303-595): 6.96e-20: 94.9: 12.50