HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: LRP10 (Q7Z4F1)
Low-density lipoprotein receptor-related protein 10 (LRP-10)
Gene: LRP10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 713
+	Hs
		564591 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		1190284 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		925392 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		951112 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		900633 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		436374 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		892455 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		LRP10_HUMAN (17-713): 8.83e-152: 459: 100.00
+	Hs
		254256 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		LRP4_HUMAN (249-518): 3.93e-29: 126: 18.86
+	Hs
		258347 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258305 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258303 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258304 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258292 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		258302 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		LRP5_HUMAN (130-297): 8.23e-22: 103: 8.72
+	Hs
		270329 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		LRP6_HUMAN (78-229): 5.54e-15: 81.5: 14.94
+	Hs
		564477 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33
+	Hs
		270285 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		LRP6_HUMAN (78-229): 5.54e-15: 81.5: 14.94
+	Hs
		925190 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33
+	Hs
		893898 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33
+	Hs
		900376 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33