HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: LYRIC (Q86UE4)
Protein LYRIC (3D3/LYRIC) (Astrocyte elevated gene-1 protein) (AEG-1) (Lysine-rich CEACAM1 co-isolated protein) (Metadherin) (Metastasis adhesion protein)
Gene: MTDH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 582
+	Hs
		951122 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		900644 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		545472 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		436380 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		LYRIC_HUMAN (1-582): 0: 949: 100.00
+	Hs
		892459 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		LYRIC_HUMAN (1-582): 0: 949: 100.00