HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: MACOI (Q8N5G2)
Macoilin (Macoilin-1) (Transmembrane protein 57)
Gene: MACO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 664
+	Hs
		951151 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MACOI_HUMAN (1-664): 2.34e-140: 426: 100.00
+	Hs
		564633 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MY18A_HUMAN (179-648): 2.66e-20: 98.3: 10.97
+	Hs
		925488 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MY18A_HUMAN (179-648): 2.66e-20: 98.3: 10.97
+	Hs
		894274 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MY18A_HUMAN (179-648): 2.66e-20: 98.3: 10.97
+	Mm
		823530 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		CTRO_MOUSE (284-664): 1.45e-14: 79.8: 11.26
+	Hs
		564564 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Mm
		823529 CDC42_MOUSE (1-191): 4.96e-82: 243: 100.00		CTRO_MOUSE (284-664): 1.45e-14: 79.8: 11.26
+	Mm
		823539 RHOA_MOUSE (5-191): 9.99e-82: 242: 53.48		CTRO_MOUSE (284-664): 1.45e-14: 79.8: 11.26
+	Hs
		724757 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MYH9_HUMAN (164-553): 5.97e-12: 71.3: 9.44
+	Hs
		148653 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		CTRO_HUMAN (313-648): 7.96e-12: 70.9: 10.17
+	Hs
		1137905 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Hs
		724776 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MYH9_HUMAN (164-553): 5.97e-12: 71.3: 9.44
+	Rn
		92842 RHOA_RAT (5-191): 9.99e-82: 242: 53.48		CTRO_RAT (313-658): 2.22e-11: 69.4: 7.80
+	Hs
		148608 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		CTRO_HUMAN (313-648): 7.96e-12: 70.9: 10.17
+	Hs
		925344 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Hs
		725125 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MYH10_HUMAN (382-660): 4.67e-09: 62.1: 9.68
+	Hs
		894116 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Hs
		725138 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MYH10_HUMAN (382-660): 4.67e-09: 62.1: 9.68
+	Hs
		951069 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72
+	Hs
		900570 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		MRCKA_HUMAN (180-613): 6.09e-09: 61.8: 13.72