HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: US6NL (Q92738)
USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)
Gene: USP6NL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007030 - Golgi organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 828
+	Hs
		564635 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		1270182 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		925494 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		951204 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		900761 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		545541 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		892524 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		1183489 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		715076 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		UBP6_HUMAN (1-554): 2.62e-120: 397: 30.45
+	Hs
		715074 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		UBP6_HUMAN (1-554): 2.62e-120: 397: 30.45
+	Hs
		564554 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Mm
		925784 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		EVI5_MOUSE (17-591): 6.72e-97: 322: 17.30
+	Hs
		1117432 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		925323 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		232655 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		TBCD4_HUMAN (1-455): 1.43e-88: 307: 19.40
+	Hs
		892404 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Ce
		975574 RAC1_CAEEL (1-191): 5.53e-85: 250: 65.97		Q23419_CAEEL (32-350): 9.62e-85: 291: 21.86
+	Sc
		580335 CDC42_YEAST (1-191): 2.69e-80: 238: 80.11		MSB4_YEAST (14-421): 8.77e-91: 296: 20.26
+	Hs
		894392 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		TBD2A_HUMAN (5-368): 1.26e-82: 285: 22.82