HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: S38A2 (Q96QD8)
Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2)
Gene: SLC38A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 31871319
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 506
+	Hs
		564648 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		S38A2_HUMAN (1-506): 7.21e-131: 391: 100.00
+	Hs
		1300306 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		S38A2_HUMAN (1-506): 7.21e-131: 391: 100.00
+	Hs
		925534 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		S38A2_HUMAN (1-506): 7.21e-131: 391: 100.00
+	Hs
		951245 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		S38A2_HUMAN (1-506): 7.21e-131: 391: 100.00
+	Hs
		900818 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		S38A2_HUMAN (1-506): 7.21e-131: 391: 100.00
+	Hs
		545567 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		S38A2_HUMAN (1-506): 7.21e-131: 391: 100.00
+	Hs
		436468 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		S38A2_HUMAN (1-506): 7.21e-131: 391: 100.00
+	Hs
		564679 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		S38A1_HUMAN (1-503): 5.78e-113: 344: 49.30
+	Hs
		1329425 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		S38A1_HUMAN (1-503): 5.78e-113: 344: 49.30
+	Hs
		925604 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		S38A1_HUMAN (1-503): 5.78e-113: 344: 49.30
+	Hs
		894414 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		S38A1_HUMAN (1-503): 5.78e-113: 344: 49.30
+	Hs
		951326 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		S38A1_HUMAN (1-503): 5.78e-113: 344: 49.30
+	Hs
		900885 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		S38A1_HUMAN (1-503): 5.78e-113: 344: 49.30
+	Hs
		545607 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		S38A1_HUMAN (1-503): 5.78e-113: 344: 49.30
+	Hs
		436500 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		S38A1_HUMAN (1-503): 5.78e-113: 344: 49.30
+	Hs
		1260632 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		S38A5_HUMAN (26-502): 3.04e-97: 303: 48.86
+	Hs
		925472 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		S38A5_HUMAN (26-502): 3.04e-97: 303: 48.86
+	Hs
		951187 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		S38A5_HUMAN (26-502): 3.04e-97: 303: 48.86
+	Hs
		900736 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		S38A5_HUMAN (26-502): 3.04e-97: 303: 48.86
+	Hs
		892509 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		S38A5_HUMAN (26-502): 3.04e-97: 303: 48.86