HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: PHB2 (Q99623)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Gene: PHB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31478661
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0032991 - protein-containing complex GO:0098978 - glutamatergic synapse
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 299
+	Hs
		925555 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		951263 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		564417 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		719140 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		646300 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		718731 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		646166 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		718676 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		718752 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		646157 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		718686 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		545232 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		646171 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		646160 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		545212 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		436164 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		646156 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93
+	Hs
		646209 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93