HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: GRWD1 (Q9BQ67)
Glutamate-rich WD repeat-containing protein 1
Gene: GRWD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 446
+	Hs
		1309054 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		GRWD1_HUMAN (1-446): 4.56e-121: 361: 100.00
+	Hs
		925565 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		GRWD1_HUMAN (1-446): 4.56e-121: 361: 100.00
+	Hs
		951274 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		GRWD1_HUMAN (1-446): 4.56e-121: 361: 100.00
+	Hs
		900844 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		GRWD1_HUMAN (1-446): 4.56e-121: 361: 100.00
+	Hs
		545586 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		GRWD1_HUMAN (1-446): 4.56e-121: 361: 100.00
+	Hs
		1183523 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		GRWD1_HUMAN (1-446): 4.56e-121: 361: 100.00
+	Hs
		900348 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Hs
		436239 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Mm
		892718 CDC42_MOUSE (1-191): 4.96e-82: 243: 100.00		LIS1_MOUSE (243-445): 5.09e-42: 155: 17.00
+	Hs
		436191 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		LIS1_HUMAN (243-445): 6.45e-42: 155: 17.00