HitPredict

Interactor 1: D4GVL8 (D4GVL8)
DNA-directed RNA polymerase subunit Rpo11 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit L)
Gene: rpoL

Interactor 2: D4GWY4 (D4GWY4)
DNA-directed RNA polymerase subunit Rpo3 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit D)
Gene: rpoD

Species: Haloferax volcanii DS2

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	34764944
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	RNA_pol_L~RNA_pol_L_2
Common GO terms	GO:0000428 - DNA-directed RNA polymerase complex GO:0003677 - DNA binding GO:0005737 - cytoplasm GO:0046983 - protein dimerization activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 96 Hv			1 259
+	Hs
		169818 RPB11_HUMAN (1-95): 3.96e-36: 120: 21.05		RPAC1_HUMAN (4-257): 6.68e-97: 289: 22.18
+	Hs
		169946 RPB1C_HUMAN (1-92): 7.86e-36: 119: 20.65		RPAC1_HUMAN (4-257): 6.68e-97: 289: 22.18
+	Hs
		169941 RPB1B_HUMAN (1-92): 8.93e-35: 116: 20.65		RPAC1_HUMAN (4-257): 6.68e-97: 289: 22.18
+	Hs
		169778 RPAC2_HUMAN (12-95): 7.45e-34: 114: 16.67		RPAC1_HUMAN (4-257): 6.68e-97: 289: 22.18
+	Hs
		583438 RPB11_HUMAN (1-95): 3.96e-36: 120: 21.05		RPB3_HUMAN (3-258): 1.81e-85: 257: 24.74
+	At
		1104914 NRPBB_ARATH (4-94): 3.97e-33: 112: 19.78		NRPB3_ARATH (5-254): 1.16e-87: 264: 25.17
+	Mm
		956874 Q3TYI2_MOUSE (1-95): 2.63e-35: 118: 20.00		RPB3_MOUSE (3-258): 1.22e-85: 258: 24.74
+	Dm
		333012 RPB11_DROME (4-95): 3.5e-35: 117: 22.83		O97183_DROME (3-258): 1.1e-85: 258: 22.57
+	At
		1104915 NRPBB_ARATH (4-94): 3.97e-33: 112: 19.78		RPD3B_ARATH (5-254): 1.05e-86: 262: 25.86
+	Hs
		583571 RPB1B_HUMAN (1-92): 8.93e-35: 116: 20.65		RPB3_HUMAN (3-258): 1.81e-85: 257: 24.74
+	Sp
		293857 RPAC2_SCHPO (13-94): 1.84e-30: 105: 18.29		RPAC1_SCHPO (4-257): 3.9e-88: 266: 22.52
+	Sc
		429651 RPAC2_YEAST (2-96): 5.3e-29: 102: 17.17		RPAC1_YEAST (4-254): 7.79e-89: 268: 24.83
+	Sc
		558050 RPB11_YEAST (1-93): 2.13e-32: 110: 25.81		RPB3_YEAST (5-258): 1.64e-81: 249: 22.14
+	Sc
		557923 RPAC2_YEAST (2-96): 5.3e-29: 102: 17.17		RPB3_YEAST (5-258): 1.64e-81: 249: 22.14
+	Dm
		1368240 RPAC2_DROME (14-94): 2.71e-19: 77: 14.82		Q9VMX3_DROME (6-257): 5.34e-89: 268: 22.48
+	Sp
		741615 RPB11_SCHPO (4-90): 1.33e-28: 101: 20.69		RPB3_SCHPO (1-257): 3.76e-80: 244: 20.70
+	Ss
		955989 RPO11_SACS2 (1-95): 2.52e-30: 104: 27.37		RPO3_SACS2 (6-257): 3.89e-72: 223: 25.37
+	Mj
		1123053 RPO11_METJA (1-93): 1.49e-25: 92.8: 29.59		RPO3_METJA (7-188): 3.44e-57: 182: 34.04