HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: FACD2 (Q9BXW9)
Fanconi anemia group D2 protein (Protein FACD2)
Gene: FANCD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 31871319
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 1451
+	Hs
		545595 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Mm
		925801 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		892728 CDC42_MOUSE (1-191): 4.96e-82: 243: 100.00		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		1194225 RHOA_MOUSE (5-191): 9.99e-82: 242: 53.48		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		951510 RHOG_MOUSE (1-191): 7.59e-82: 242: 60.73		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		983318 RAC2_MOUSE (1-191): 1.1e-80: 239: 69.27		FACD2_MOUSE (1-1439): 0: 1973: 74.76