HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: ZDHC5 (Q9C0B5)
Palmitoyltransferase ZDHHC5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375)
Gene: ZDHHC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31871319, 31402609
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005886 - plasma membrane GO:0016020 - membrane GO:0045335 - phagocytic vesicle GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 715
+	Hs
		564675 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		ZDHC5_HUMAN (1-715): 2.39e-127: 396: 100.00
+	Hs
		1318848 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		ZDHC5_HUMAN (1-715): 2.39e-127: 396: 100.00
+	Hs
		925592 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ZDHC5_HUMAN (1-715): 2.39e-127: 396: 100.00
+	Hs
		951307 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ZDHC5_HUMAN (1-715): 2.39e-127: 396: 100.00
+	Hs
		900870 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ZDHC5_HUMAN (1-715): 2.39e-127: 396: 100.00
+	Hs
		545599 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		ZDHC5_HUMAN (1-715): 2.39e-127: 396: 100.00
+	Hs
		436492 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		ZDHC5_HUMAN (1-715): 2.39e-127: 396: 100.00
+	Hs
		892578 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		ZDHC5_HUMAN (1-715): 2.39e-127: 396: 100.00
+	Hs
		564731 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		ZDHC8_HUMAN (1-715): 1.05e-79: 271: 44.52
+	Hs
		1330983 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		ZDHC8_HUMAN (1-715): 1.05e-79: 271: 44.52
+	Hs
		925720 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ZDHC8_HUMAN (1-715): 1.05e-79: 271: 44.52
+	Hs
		894577 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ZDHC8_HUMAN (1-715): 1.05e-79: 271: 44.52
+	Hs
		951451 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ZDHC8_HUMAN (1-715): 1.05e-79: 271: 44.52
+	Hs
		901039 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ZDHC8_HUMAN (1-715): 1.05e-79: 271: 44.52
+	Hs
		545693 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		ZDHC8_HUMAN (1-715): 1.05e-79: 271: 44.52
+	Hs
		1139946 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		ZDH20_HUMAN (9-314): 7.71e-66: 223: 21.02
+	Hs
		925350 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ZDH20_HUMAN (9-314): 7.71e-66: 223: 21.02
+	Hs
		900575 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ZDH20_HUMAN (9-314): 7.71e-66: 223: 21.02
+	Hs
		545436 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		ZDH20_HUMAN (9-314): 7.71e-66: 223: 21.02
+	Hs
		892428 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		ZDH20_HUMAN (9-314): 7.71e-66: 223: 21.02