HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: TMX1 (Q9H3N1)
Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein)
Gene: TMX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 280
+	Hs
		925609 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		TMX1_HUMAN (1-280): 1.13e-79: 243: 100.00
+	Hs
		951331 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		TMX1_HUMAN (1-280): 1.13e-79: 243: 100.00
+	Hs
		900889 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		TMX1_HUMAN (1-280): 1.13e-79: 243: 100.00
+	Hs
		436502 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		TMX1_HUMAN (1-280): 1.13e-79: 243: 100.00
+	Hs
		894198 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DJC10_HUMAN (64-264): 2.26e-14: 74.8: 10.95
+	Hs
		900668 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		DJC10_HUMAN (64-264): 2.26e-14: 74.8: 10.95